Characteristic Details
Active Ingredients Sildenafil 100 mg, Fluoxetine 60 mg
Form Tablet
Intended Use Treatment of erectile dysfunction and premature ejaculation
Prescription Required Yes
Learn More About Malegra FXT

Chemical Structure

The chemical structure of Malegra FXT reveals its dual composition. Sildenafil, a phosphodiesterase type 5 (PDE5) inhibitor, comprises one component. It includes a pyrazolopyrimidinone core. This core interlinks with various functional groups enhancing its vasodilatory effects. Fluoxetine, an SSRI, constitutes the second component. It has a benzene ring structure. This structure facilitates its role in serotonin modulation.

Both compounds retain distinct yet complementary roles. Their interaction forms a potent therapeutic agent. The combination in Malegra FXT targets erectile dysfunction (ED) and premature ejaculation (PE). These chemical properties serve as the foundation of its pharmacological action.

Mechanism of Action

Malegra FXT combines the effects of two pharmacological pathways. Sildenafil, at a dosage of 100 mg, targets the PDE5 enzyme. It prevents cGMP breakdown. This enzyme blockade enhances blood flow to the penile region. Consequently, it facilitates erection maintenance. Fluoxetine, at 60 mg, modulates serotonin levels. It delays ejaculation by prolonging the synaptic activity of serotonin.

This synergistic mechanism addresses two critical sexual dysfunctions. Enhancing erectile function while managing ejaculation timing optimizes sexual performance. Malegra FXT offers a unique dual-action approach. Further insights are available on scientific platforms.

Malegra FXT Contraindications

Certain conditions preclude the use of Malegra FXT. Patients with cardiovascular disorders face elevated risks. Uncontrolled hypertension or recent myocardial infarction renders usage unsafe. Severe hepatic or renal impairments also contraindicate administration.

Malegra FXT should not be combined with nitrates. This combination leads to severe hypotension. Additionally, individuals with a known hypersensitivity to sildenafil or fluoxetine must avoid this medication.

Malegra FXT Interactions

Interactions with other pharmaceuticals may influence Malegra FXT efficacy. Nitrate-containing medications pose a significant risk. Concomitant use leads to adverse cardiovascular events. Alpha-blockers also affect blood pressure control. Caution is essential when used together.

  • Antidepressants: Other SSRIs or SNRIs intensify fluoxetine effects.
  • Antibiotics: Certain macrolides increase sildenafil concentration.
  • Antifungals: Azoles affect sildenafil metabolism.

Adverse Effects

Malegra FXT’s adverse effects range in severity. Common issues include headache, flushing, and dyspepsia. These effects stem from sildenafil’s vasodilatory action.

Fluoxetine may induce nausea or insomnia. Psychological effects like anxiety or mood swings occur. Less frequent but serious adverse reactions require medical attention. Vision changes or prolonged erections (>4 hours) necessitate immediate consultation.

Where to Buy Malegra FXT Online

Purchasing Malegra FXT online requires caution. Licensed pharmacies ensure product authenticity. A prescription verifies medical suitability. Ensure sources adhere to FDA regulations.

Explore verified platforms offering legitimate products. Always verify website credentials. Such diligence ensures safe acquisition.

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